What is Juvenile Myelomonocytic Leukemia (JMML)?
Juvenile myelomonocytic leukemia (JMML) is a rare cancer of the blood that affects young children. JMML happens when types of white blood cells called monocytes and myelocytes do not mature normally. JMML can happen spontaneously (by chance) or can be associated with other genetic disorders in some children.
Diagnosis
In addition to a complete medical history and physical examination, diagnostic procedures for juvenile myelomonocytic leukemia may include:
- Blood tests and physical examination
- Bone marrow aspiration and/or biopsy.
- Genetic mutation testing.
Treatment
The only known successful treatment for JMML is bone marrow transplantation (hematopoietic stem cell transplantation). Children may also be treated with chemotherapy prior to a bone marrow transplant.